2). Dopaminergic pathway

Another way the human body can be made to produce more hGH is by increasing the levels of a neurotransmitter called “dopamine” in the human brain.

Dopamine is a crucial brain chemical associated with motor performance (physical movements) and general motivation, arousal, excitement. One reason why the aging adults find it hard to move their body, like finding it difficult to get out of chair or bed, having low energy to walk or run, etc. is that they have low levels of dopamine.

This natural chemical is also taking part in other areas like it enables you to learn new skills or gain new insight and it governs the encoding of stimulating elements present in the world into the brain.

Anything you enjoy in life, like food, sex, entertainment activities, video games, fun, or even popcorn is somewhat encoded in your brain via dopamine.

So, dopamine is basically an “encoded” signal of joy.


Practically all drugs of abuse, like heroin and other opiates, alcoholic beverages, benzoylmethylecgonine, cocaine, amphetamine and nicotine activate dopamine neuronal systems.

Dopamine is a giant powerful chemical and it is what provides you with the energy lift to get out of bed after you awake and continue with daily routine with motivation.

Additionally, it works a big part in the libido and sexual performance.

One of the main functions of dopamine produced by the hypothalamus is to slow down the secretion of prolactin from the anterior lobe of the pituitary gland, states the Massachusetts General Hospital Neuroendocrine Clinical Center.

Prolactin lowers testosterone levels in men and too much prolactin can cause a pituitary tumor.

Studies confirm that dopamine acts as a modulating (balancing) hormone in the brain and protects and enhances the pituitary function of the brain.

The biggest benefit of dopamine though is that it’s a powerful growth hormone booster.

Interestingly, it’s also connected to testosterone in men. Insufficient dopamine protection of the anterior pituitary gland can also result in hypogonadism in men, reducing their libido, minimizing their manufacturing of sperm and quite possibly leading to erectile dysfunction.

Obstruction of dopamine to the pituitary may also result in a condition called gynecomastia or breast enlargement in men.

To increase growth hormone via Dopaminergic pathway, you need

– More calcium

The exact mechanism how dopamine enhances hGH is still being researched, however experts believe that it does so by increasing another hormone called GHRH which acts by increasing intracellular calcium concentration in pituitary cells which secrete growth hormone.

The release of GHRH is elevated during the slow sleep. It is triggered by hypoglycemia, arginine, dopamine, serotonin, alpha-2-mimetics like clonidine which was employed for treating short stature.

The keywords for us here are :- arginine, dopamine, serotonin.

We’ll talk about serotonin in warming/cooling equilibrium pathway.

– Increase in Dopamine levels

One of the best supplements to increase dopamine naturally is L-tyrosine. This supplement is being used as a nootropic as well, and its users have consistently reported dramatic energy, increased motivation and vigor.


Tyrosine, is not an essential amino acid because it can be produced from the amino acid phenylalanine. It is transformed into dopamine and norepinephrine.

The use of tyrosine supplements leads to alertness and mental arousal. Tyrosine works in a smooth, consistent, efficient way, to improve alertness and focus, along with mood, enhances dopamine in the body and thereby increases hGH.

Another supplement that is incredibly powerful in enhancing dopamine, mental focus, alertness and physical energy is Alpha GPC.

Some really interesting research has been done on its applications in anti aging and bodybuilding.

– Deep sleep at night

deep sleep

Dopamine encourages the pituitary gland to produce and secrete growth hormone. The release of growth hormone is activated by GHRH, growth hormone releasing hormone, also referred to as somatocrinin, secreted by the hypothalamus in a pulsatile mode and in line with a circadian cycle that reaches its peak throughout the slow sleep.

To ensure you get a really deep sleep and dopamine actually works to increase your HGH levels, you’ve got to understand the warming/cooling equilibrium pathway.