Master List of Top recommended IGF-1 Supplements for Bodybuilders & Athletes

IGF-1 (Insulin-like Growth Factor 1) is a powerful growth hormone that plays a crucial role in muscle repair, recovery, and hypertrophy. Bodybuilders and athletes turn to IGF-1 supplements to accelerate muscle growth, reduce recovery time, and enhance overall performance.

Whether derived from natural sources like deer antler velvet or in peptide form like IGF-1 LR3, these supplements can support lean muscle mass and fat metabolism. However, choosing the right IGF-1 supplement is essential to maximize benefits while minimizing risks. In this guide, we’ll explore the best IGF-1 supplements, their benefits, and how to use them safely for optimal results.

• Best IGF-1/deer antler velvet for bodybuilders, athletes: HyperGH 14X
• Best IGF-1/deer antler velvet for anti-aging, overall health & wellness: Genf20 Plus

1). HyperGH 14X – The #1 IGF-1 Supplement for Bodybuilders & Athletes

Review: Powerful Natural IGF-1 and HGH booster for gains. HyperGH 14X is a powerful, science-backed formula designed to naturally boost IGF-1 and HGH levels. With clinically dosed ingredients, it supports muscle growth, recovery, and overall performance, making it an excellent choice for bodybuilders and athletes looking for a safe and effective anabolic edge.

As the creator of PowerandBulk’s 30-Day Anabolic Alchemy program, I’ve tested and reviewed countless IGF-1 boosting supplements. If you’re serious about muscle growth, faster recovery, and maximizing HGH production naturally, HyperGH 14X stands out as the top choice. Unlike synthetic IGF-1 injections, which come with legal and safety concerns, HyperGH 14X uses a scientifically backed formula to stimulate your body’s own natural production of HGH and IGF-1.

The same company also offers a product for the anti-aging enthusiasts : Genf20 Plus , an HGH supplement that comes with deer antler velvet extract/natural growth factors.

For maximum results, growth & recovery, I recommend stacking these supplements with PrimeMale and Tongkat Ali. For full list of my recommended supplements & products, click here.

What Makes HyperGH 14X Unique? (USP Breakdown)

Most HGH-boosting supplements are either underdosed or rely on a single ingredient. HyperGH 14X, however, is stacked with 15+ clinically proven compounds that work synergistically to trigger HGH release and IGF-1 production. It’s one of the few supplements on the market that combines colostrum (rich in IGF-1) and deer antler velvet (natural IGF-1 source) alongside potent amino acids like L-Arginine and L-Ornithine, which are proven HGH boosters.

Unlike the typical capsules or powders, HyperGH 14x comes with enteric coated tablets which prevent the IGF-1 breakdown by stomach acid, ensuring the maximum amount of growth factors from colostrum, deer antler velvet reaches your system. Besides, this also comes with Alpha-GPC spray, one of the most powerful and potent HGH/IGF-1 boosters and nootropics for workout.

Why I Recommend It for My Clients:

• Double-Action Formula – Boosts both HGH and IGF-1 naturally.
• Day & Night Optimization – Supports 24/7 HGH release with AM & PM dosing.
• No Needles, No Prescriptions – Unlike IGF-1 injections, it’s completely natural.
• Muscle Growth & Recovery – Enhances protein synthesis and post-workout recovery.
• Sleep & Testosterone Support – Includes GABA, L-Glycine, and Tribulus Terrestris to optimize anabolic hormone levels.

Who Is HyperGH 14X Best For?

This supplement is ideal for:
✔️ Bodybuilders looking for a natural HGH/IGF-1 alternative without the risks of injections.
✔️ Athletes & Lifters who want faster recovery and lean muscle gains.
✔️ Men Over 30 experiencing HGH decline and looking to maintain peak performance.
✔️ Fat Loss Seekers who want to burn fat while preserving muscle mass.

Pros & Cons

✅ Pros:
✔️ Natural HGH/IGF-1 booster – No synthetic hormones.

✔️ Enteric coated tablets which prevent the ingredients breakdown by stomach acid, which means maximum absorption of natural growth factors- IGF-1

✔️ Packed with clinically researched ingredients.
✔️ Supports muscle growth, fat loss, and recovery.
✔️ Includes 200mg. colostrum & 200mg. deer antler velvet extract for direct IGF-1 support.

✔️ Comes with Alpha-GPC spray, one of the most potent HGH/IGF-1 boosters and nootropics for workout
✔️ Legal & safe – No injections or prescriptions needed.

❌ Cons:
✘ Results take time – Requires 6+ weeks of consistent use.
✘ Slightly premium-priced compared to basic HGH supplements.
✘ Not a direct synthetic IGF-1 replacement for extreme cases.

If you want to supercharge your IGF-1 and HGH levels naturally, HyperGH 14X is your best bet. It’s an essential tool in my Anabolic Alchemy program because it combines science-backed ingredients in precise dosages to fuel muscle growth, recovery, and performance.

Here is my detailed evaluation:-

IGF-1 Boosting Effectiveness: 4 /5 – Contains colostrum (rich in IGF-1) and deer antler velvet, both known to support IGF-1 levels naturally. While not as direct as IGF-1 peptides, it provides a strong indirect boost through HGH stimulation.

HGH Stimulation: 4.5/5 – Formulated with L-Arginine, L-Ornithine, GABA, and Anterior Pituitary Powder, which are all proven HGH boosters that work synergistically. One of the best non-injection options for increasing HGH.

Muscle Growth & Recovery: 4.5/5 – High doses of BCAAs, L-Glutamine, and L-Glycine make this great for post-workout recovery and muscle repair, but it’s not as rapid as synthetic IGF-1 injections.

Fat Loss & Lean Muscle Retention: 4/5 – Helps preserve lean muscle while cutting due to its HGH-boosting properties, but results take longer compared to direct IGF-1 injections or more aggressive fat-burning stacks.

Strength & Performance Enhancement: 4/5 – Improves endurance, strength, and workout capacity over time, but requires consistency—not an immediate strength booster like creatine.

Ingredient Quality & Dosage – 5/5 – Clinically dosed amino acids & growth factors, with research-backed effectiveness. No fillers or underdosed ingredients.

Safety & Side Effects – 5/5 – 100% natural & legal alternative to IGF-1 injections. No major side effects reported.

Value for money; 4/5 – Premium formula with proven ingredients, but slightly pricey compared to basic HGH boosters. Worth it for serious bodybuilders & athletes.

#2 Pick: Bucked Up Deer Antler Velvet Spray – A Fast-Acting IGF-1 Booster

Review: Fast-absorbing IGF-1 spray for recovery. Bucked Up Deer Antler Velvet Spray provides a fast-absorbing IGF-1 boost through its sublingual formula, making it a great option for athletes and lifters seeking quicker muscle recovery and performance enhancement. While it’s not as potent as direct IGF-1 injections, its natural ingredients and testosterone-supporting compounds make it a well-rounded choice.

When it comes to fast-acting, convenient IGF-1 support, Bucked Up Deer Antler Velvet Spray deserves the #2 spot on my list. As a highly bioavailable spray, it bypasses digestion and delivers deer antler velvet-derived IGF-1 directly into the bloodstream. Unlike the typical capsules or powders, this sublingual delivery method ensures quicker absorption and enhanced effectiveness.

What Makes Bucked Up Deer Antler Velvet Spray Unique? (USP Breakdown)

Many IGF-1 supplements rely on indirect HGH stimulation, but Bucked Up provides a direct source of IGF-1 from deer antler velvet extract. This makes it an ideal choice for athletes, lifters, and recovery-focused users who want a more immediate boost in muscle repair, strength, and endurance. The addition of L-Arginine, Tribulus Terrestris, and Epimedium further supports testosterone production, circulation, and muscle performance—giving it a dual anabolic effect beyond just IGF-1.

Why I Recommend It for My Clients:

• Fast-Absorbing Sublingual Formula – Faster onset compared to pills or powders.
• Direct IGF-1 Source – Deer antler velvet extract delivers real IGF-1 naturally.
• Testosterone & Circulation Boost – Includes L-Arginine, Tribulus, and Epimedium for improved performance.
• Joint & Recovery Support – IGF-1 enhances cartilage, tendon, and muscle repair.
• All-Natural Formula – No synthetic hormones, just bioavailable growth factors.

Who Is Bucked Up Deer Antler Velvet Best For?

This supplement is best for:
✔️ Athletes & Lifters who want faster recovery and joint repair.
✔️ Bodybuilders looking for natural IGF-1 support to enhance lean muscle growth.
✔️ Strength Trainers who need improved circulation and endurance for intense workouts.
✔️ Active Aging Individuals who want to maintain muscle mass, strength, and joint health.

Pros & Cons

✅ Pros:
✔️ Fast-absorbing sublingual formula – Quick action compared to capsules.
✔️ Direct IGF-1 from deer antler velvet – No need to rely solely on HGH stimulation.
✔️ Supports testosterone & circulation – L-Arginine, Tribulus, and Epimedium boost nitric oxide & hormone production.
✔️ Great for joint & tissue repair – IGF-1 plays a key role in healing and recovery.
✔️ No synthetic hormones – Completely natural and safe.

❌ Cons:
✘ Proprietary blend – Exact dosages of ingredients aren’t disclosed.
✘ Not as potent as IGF-1 injections – More of a mild to moderate IGF-1 boost.
✘ Slightly expensive for a spray – But worth it for those who prefer liquid formulas.

#3 Pick: Hi-Tech Pharmaceuticals Pro IGF-1 – Targeted Growth Factor Support

Review: Pure IGF-1 support for muscle recovery. Hi-Tech Pharmaceuticals Pro IGF-1 delivers a straightforward, direct dose of IGF-1 from NXP-GF Whey Protein Isolate, making it a great addition for bodybuilders and athletes looking to enhance muscle recovery and performance. While not as potent as IGF-1 injections, it’s a solid option for those seeking pure IGF-1 support without unnecessary additives.

If you’re looking for a potent, no-nonsense IGF-1 supplement, Hi-Tech Pharmaceuticals Pro IGF-1 earns the #3 spot on my list. Unlike generic HGH boosters that rely on amino acid stacks, this supplement provides direct IGF-1 extracted from NXP-GF Whey Protein Isolate. With 20mcg of pure IGF-1 per serving, this is one of the closest things to actual IGF-1 administration in a supplement form.

What Makes Hi-Tech Pharmaceuticals Pro IGF-1 Unique? (USP Breakdown)

Most IGF-1 supplements stimulate HGH production, which then leads to increased IGF-1 levels. Pro IGF-1 skips that step, delivering IGF-1 directly from an advanced whey protein isolate extraction process. This makes it a solid option for bodybuilders and athletes who want to enhance muscle growth, recovery, and performance without relying on HGH boosters.

Why I Recommend It for My Clients:

• Direct IGF-1 Source – No waiting for HGH conversion.
• Ultra-Pure NXP-GF Whey Extract – Highly bioavailable for muscle and tissue repair.
• Muscle Growth & Recovery Focused – Ideal for those prioritizing hypertrophy and recovery.
• No Complex Stacks – A great choice for those who already use HGH boosters or testosterone enhancers and just need extra IGF-1 support.

Who Is Hi-Tech Pharmaceuticals Pro IGF-1 Best For?

This supplement is perfect for:
✔️ Bodybuilders & Strength Athletes who want a direct IGF-1 source to accelerate gains.
✔️ Hard Gainers who struggle with muscle recovery and lean mass development.
✔️ Experienced Lifters who already take testosterone or HGH boosters but need additional IGF-1 support.
✔️ Aging Athletes looking to enhance recovery and joint health.

Pros & Cons

✅ Pros:
✔️ Direct IGF-1 content – No need to rely on precursors.
✔️ Supports muscle growth & recovery – IGF-1 is key for hypertrophy.
✔️ No unnecessary fillers – A straightforward, high-purity formula.
✔️ Pairs well with other hormone boosters – Ideal for stacking.

❌ Cons:
✘ Lower IGF-1 dose than injections – At 20mcg, it’s effective but not as strong as pharmaceutical IGF-1 injections.
✘ No additional HGH-boosting ingredients – Works best as part of a broader muscle-building stack.
✘ Limited versatility – Not ideal for testosterone optimization or fat loss, just IGF-1 support.

#4 Pick: Primal Muscle 191XT Oral Spray – A Well-Rounded IGF-1 & Testosterone Booster

Review: Decent IGF-1 spray with testosterone-boosting support! Primal Muscle 191XT Oral Spray offers a balanced blend of IGF-1 from deer antler velvet and natural testosterone boosters like Tribulus and Longjack. While it’s not the most IGF-1-concentrated option, its dual-action formula makes it a strong choice for those seeking both muscle growth and hormonal support. However, the use of proprietary blend is concerning and exact dosage of IGF-1 boosting compounds is unknown. Users report very mixed results.

If you’re looking for a dual-action formula that supports both IGF-1 and testosterone, Primal Muscle 191XT Oral Spray earns the #4 spot on my list. This liquid formula combines Deer Antler Velvet (a natural IGF-1 source) with key testosterone-enhancing ingredients, making it a great choice for athletes who want strength, endurance, and muscle recovery in one product.

What Makes Primal Muscle 191XT Unique? (USP Breakdown)

Unlike pure IGF-1 supplements, 191XT takes a hybrid approach—not only does it deliver IGF-1 through Deer Antler Velvet, but it also includes a powerful testosterone-supporting blend with Epimedium (Horny Goat Weed), Tribulus, and Tongkat Ali (Longjack). This means you get the muscle-building and recovery benefits of IGF-1, along with a natural anabolic hormone boost for strength and performance.

Why I Recommend It for My Clients:

• Liquid Formula for Faster Absorption – Sublingual sprays work faster than pills.
• IGF-1 + Testosterone Synergy – Supports muscle growth, endurance, and hormone balance.
• Deer Antler Velvet for Natural IGF-1 – Helps with recovery, lean mass, and tissue repair.
• Testosterone Boosting Trio – Epimedium, Tribulus, and Longjack support strength, libido, and energy.
• L-Arginine for Performance – Improves circulation, nitric oxide levels, and muscle pumps.

Who Is Primal Muscle 191XT Best For?

This supplement is ideal for:
✔️ Athletes & Lifters who want faster recovery and enhanced endurance.
✔️ Men Over 30 looking for natural testosterone & IGF-1 support.
✔️ Strength Trainers who want muscle growth and better performance.
✔️ Active Individuals looking to maintain hormonal balance, energy, and recovery.

Pros & Cons

✅ Pros:
✔️ Fast-absorbing spray – Quicker effects than capsules or powders.
✔️ Dual-action formula – IGF-1 + testosterone boost in one product.
✔️ Great for recovery & endurance – Supports muscle growth & fatigue reduction.
✔️ All-natural formula – No synthetic hormones or artificial ingredients.
✔️ Easy to stack – Can be combined with HGH boosters or fat burners.

❌ Cons:
✘ Proprietary blend – Exact IGF-1 content not disclosed.
✘ Not as strong as direct IGF-1 supplements – Better as a hybrid support formula.
✘ Results take time – Expect to use for 6+ weeks for full benefits.

#5 Pick: Thrive Lab IGF-1 Tablets – High Dose, But Lacks Proof

Review: Ultra-high-dose IGF-1 tablets, but unproven! Thrive Lab IGF-1 Tablets boast an industry-leading 1000mcg IGF-1 dose, making them one of the most potent supplements on paper. However, the lack of real-world reviews, absence of an enteric coating for proper absorption, and unverified efficacy make this a high-risk, high-reward choice for serious lifters.

If you’re searching for an ultra-high-dose IGF-1 supplement, Thrive Lab IGF-1 might catch your eye with its massive 1000mcg per serving claim. That’s 7x more potent than most IGF-1 supplements, making it one of the strongest on-paper IGF-1 formulas available. But does the science and real-world effectiveness back up the numbers? That’s where this supplement falls short.

What Makes Thrive Lab IGF-1 Unique? (USP Breakdown)

The biggest selling point? A massive 1000mcg IGF-1 dose per serving. This is significantly higher than standard IGF-1 supplements, which typically range from 20mcg to 200mcg. However, real-world feedback is lacking, and there’s no enteric coating on the tablets, which could reduce IGF-1 absorption since stomach acid might break it down before it reaches the intestines.

Why I Recommend It (With Caution):

• Highest IGF-1 dose on the list – If the numbers are accurate, this is the most potent option.
• Convenient Tablet Form – No need for sprays or sublingual absorption.
• Simple Formula, No Fillers – Just IGF-1, making it easy to stack with other supplements.

Who Is Thrive Lab IGF-1 Best For?

✔️ Experienced Lifters & Athletes who want maximum IGF-1 dosage.
✔️ Hard Gainers looking for the strongest IGF-1 support.
✔️ People Willing to Experiment with a lesser-known product.
✔️ Stackers who already take HGH/Testosterone boosters and want an IGF-1 add-on.

Pros & Cons

✅ Pros:
✔️ Highest IGF-1 dose on the market – 1000mcg per tablet.
✔️ Simple & direct formula – No unnecessary additives.
✔️ Capsule form for easy use – No messy sprays or liquids.

❌ Cons:
✘ Lack of real user reviews – Very little feedback on effectiveness.
✘ No enteric coating – IGF-1 may be destroyed by stomach acid before absorption.
✘ Expensive for an unproven product – High price without clinical backing.

Which IGF-1 supplement should I choose?

✔️ For bodybuilders & strength athletes → HyperGH 14X or Hi-Tech Pharmaceuticals Pro IGF-1
✔️ For endurance & competitive athletes → Bucked Up Deer Antler Velvet Spray
✔️ For men over 30 & anti-aging → HyperGH 14X
✔️ For hard gainers struggling with muscle growth → Hi-Tech Pharmaceuticals Pro IGF-1
✔️ For recovery & injury healing → HyperGH 14X or Bucked Up Deer Antler Velvet Spray
✔️ For those seeking both IGF-1 & testosterone boost → HyperGH 14X or Primal Muscle 191XT Oral Spray
✔️ For experimental users who want the highest IGF-1 dose → Thrive Lab IGF-1 Tablets
✔️ For users who want convenience & easy supplementation → Bucked Up Deer Antler Velvet Spray

IGF-1 supplementation isn’t a one-size-fits-all solution. Different users have different needs based on their goals, fitness level, age, and performance demands. Below are consumer segments along with the best product recommendations for each.

1. Bodybuilders & Strength Athletes

(Looking for maximum muscle growth, strength, and recovery support)

Best Product: HyperGH 14X
✅ Why? This is a full-spectrum IGF-1 & HGH booster, which naturally enhances anabolic hormone production to maximize muscle growth, endurance, and post-workout recovery.

Alternative: Hi-Tech Pharmaceuticals Pro IGF-1 – If you want a direct IGF-1 source without additional HGH-boosting ingredients.

2. Competitive Athletes (Endurance & Power Sports)

(Seeking faster recovery, improved endurance, and injury prevention)

Best Product: Bucked Up Deer Antler Velvet Spray
✅ Why? The sublingual spray ensures rapid absorption, delivering IGF-1 and circulation-boosting compounds like L-Arginine to help with endurance, strength, and post-training recovery.

Alternative: Primal Muscle 191XT Oral Spray – If you want a mix of IGF-1 and testosterone-boosting ingredients for added power.

3. Men Over 30 (Anti-Aging, Hormonal Balance & Lean Muscle Retention)

(Looking to slow aging, maintain lean muscle, and optimize hormones naturally)

Best Product: HyperGH 14X
✅ Why? As natural HGH levels decline with age, this formula helps stimulate IGF-1 and HGH production, improving muscle retention, fat metabolism, and overall vitality.

Alternative: Primal Muscle 191XT Oral Spray – If you also want testosterone support alongside IGF-1 benefits.

4. Hard Gainers & Ectomorphs (Struggling to Build Muscle & Strength)

(Looking for a strong IGF-1 boost to enhance protein synthesis & muscle growth)

Best Product: Hi-Tech Pharmaceuticals Pro IGF-1
✅ Why? Provides direct IGF-1 from whey isolate, which is ideal for those struggling to gain muscle despite heavy training & eating high-protein diets.

Alternative: Thrive Lab IGF-1 Tablets – If you want a high-dose IGF-1 option, but keep in mind the absorption concerns.

5. Recovery & Injury Healing (Joint, Tendon & Tissue Repair)

(Athletes, older individuals, or lifters recovering from injuries)

Best Product: Bucked Up Deer Antler Velvet Spray
✅ Why? Deer antler velvet contains IGF-1, which supports joint, tendon, and cartilage repair, making it one of the best options for injury recovery.

Alternative: HyperGH 14X – If you want HGH stimulation for long-term recovery benefits.

6. Individuals Looking for a Natural Testosterone & IGF-1 Combo

(Those who want IGF-1 benefits but also need a testosterone boost for energy, libido, and strength)

Best Product: Primal Muscle 191XT Oral Spray
✅ Why? It combines IGF-1 with testosterone-enhancing compounds like Tribulus, Epimedium, and Longjack, making it a great dual-action muscle & hormone booster.

Alternative: Bucked Up Deer Antler Velvet Spray – If you prefer a more direct IGF-1 spray with mild testosterone support.

7. Experimental Users (Seeking the Highest Possible IGF-1 Dose)

(For those willing to take risks on unproven but high-dose formulas)

Best Product: Thrive Lab IGF-1 Tablets
✅ Why? At 1000mcg per serving, it claims 7x more potency than most IGF-1 supplements, making it the highest-dose IGF-1 product available.

Alternative: Hi-Tech Pharmaceuticals Pro IGF-1 – If you want a direct IGF-1 source but with a more established brand & research-backed formulation.

8. Those Looking for Convenience & Ease of Use

(Users who don’t want injections, powders, or complex stacks)

Best Product: Bucked Up Deer Antler Velvet Spray
✅ Why? The spray format is fast-absorbing and easy to use, making it a hassle-free alternative to pills and powders.

Alternative: Primal Muscle 191XT Oral Spray – If you want a similar spray formula but with added testosterone support.