Introduction to MK-677 in Bodybuilding

MK-677, also known as Ibutamoren, has been making waves in the bodybuilding community. It’s not a steroid, nor is it a traditional performance-enhancing drug. It’s a growth hormone secretagogue, which means it stimulates the body to produce more growth hormone. This unique mechanism of action has made it a hot topic among bodybuilders and fitness enthusiasts alike.

The popularity of MK-677 in bodybuilding is not surprising. In a world where everyone is looking for an edge, MK-677 offers a unique proposition.

It promises the benefits of increased growth hormone levels without the need for injections or the side effects associated with traditional anabolic steroids.

It’s like having your cake and eating it too, and who wouldn’t want that?

Also Read: Best MK-677 Brands for sale

Key Takeaways: MK-677 for Bodybuilding

1. MK-677 comes with its own set of caveats, it offers several benefits that can be particularly useful for bodybuilders, including increased growth hormone levels & its muscle building effects, increased water retention for better mobility & lubrication of joints, increased appetite for bulking benefits, and improved sleep quality for better recovery from workouts.


2. MK-677 can cause lethargy, especially when taken in the morning. Many bodybuilders prefer to take it at night to aid in better sleep. It’s beneficial to take days off from MK-677 to combat the lethargic feeling. A common schedule is five days on and two days off.

3. Cycling off after a certain period, such as ten weeks, is recommended to give the body a break.

4. Monitoring blood glucose is crucial when taking MK-677, as elevated blood glucose over a long period can lead to diabetes. Supplements like fish oil and BERBERINE can help combat the increase in insulin resistance caused by MK-677.

5. MK-677 significantly increases hunger, which can be beneficial for bulking but detrimental for cutting. It’s not typically recommended for cutting phases due to increased hunger and water retention, but it can be beneficial during bulking phases.

6. MK-677 can cause water retention, which is most noticeable the day after taking a dose. If a user wants to look dry for a certain event, it’s recommended to take a couple of days off from MK-677.

7. Despite some drawbacks & potential side effects, many users find the benefits of MK-677, such as improved sleep, increased muscle fullness, and assistance in muscle building, to outweigh the negatives.

8. It’s important to get MK-677 prescribed from a trusted source to ensure its quality and safety. Regular monitoring and consultation with a healthcare professional is also recommended.

9. Individual experiences with MK-677 can vary greatly, and it’s important to listen to your body and adjust dosage or discontinue use if necessary.

What is MK-677?


MK-677, or Ibutamoren, is a potent, long-acting, orally-active, selective, and non-peptide agonist of the ghrelin receptor and a growth hormone secretagogue, mimicking the growth hormone (GH)-stimulating action of the endogenous hormone ghrelin. It has been shown to increase the secretion of several hormones including GH and insulin-like growth factor 1 (IGF-1) and produces sustained increases in the plasma levels of these hormones without affecting cortisol levels.

In simpler terms, MK-677 tricks your brain into thinking it’s hungry (even when you’re not), which in turn triggers your brain to release growth hormone. This is the same natural process that happens when you fast or sleep, both of which are times when your body naturally releases growth hormone.

Benefits of MK-677 in Bodybuilding


MK-677 has several benefits that make it a favorite among bodybuilders. Let’s break them down:

  1. Muscle-building properties

MK-677 is known for its potent muscle-building properties. It achieves this by increasing levels of growth hormone and IGF-1 in the body, both of which play a crucial role in muscle growth and development. A study published in the Journal of Clinical Endocrinology and Metabolism found that MK-677 enhances the secretion of growth hormone and IGF-1, leading to increased muscle mass.


  1. Reduction in muscle wasting:

MK-677 is not just about building muscle; it’s also about preserving it. It has been shown to reduce muscle wasting, particularly in individuals who are in a caloric deficit. This makes it an excellent tool for bodybuilders during the cutting phase when the goal is to lose fat while preserving as much muscle as possible.

3. Improved bone density:

MK-677 doesn’t just stop at muscles; it also helps improve bone density. This is particularly important for bodybuilders and athletes, as increased bone density can lead to improved performance and reduced risk of injury. A study published in the Journal of Bone and Mineral Research found that MK-677 improves bone density in postmenopausal osteoporotic women.

4.Anti-aging properties

MK-677 has been touted for its anti-aging properties. This is because growth hormone and IGF-1, both of which are increased by MK-677, are known to have anti-aging effects. They can improve skin health, boost energy levels, and enhance recovery, all of which are beneficial for bodybuilders and athletes.

5.Increased Water Retention:

One of the effects of MK-677 is that it increases water retention in the body. While this might be seen as a drawback for those looking to maintain a lean and dry physique, it can actually be beneficial for bodybuilders in several ways.

Firstly, increased water retention can contribute to increased strength. This is because water is stored in the muscle cells, leading to a greater volume of muscle which can lead to increased strength and power output during workouts.

Secondly, water acts as a lubricant in the body, including in the joints and tendons. This means that with increased water retention, your joints and tendons are better lubricated, which can help prevent injuries when moving heavy weights. This is particularly beneficial for bodybuilders who often put a lot of strain on their joints and tendons during intense workouts.

6. Increases Appetite

Another effect of MK-677 is that it can significantly increase appetite. This is particularly beneficial for bodybuilders who are in a bulking phase and need to consume many calories to support muscle growth.

Getting enough calories can often be a challenge for bodybuilders, especially when they need to consume a lot more than their body naturally requires.

By increasing appetite, MK-677 can make it easier to consume the necessary amount of food to meet these high caloric needs, thereby supporting muscle growth and recovery.

7. Induces REM Sleep

MK-677 has also been found to improve the quality of sleep, particularly by increasing the amount of REM (Rapid Eye Movement) sleep. REM sleep is a stage of sleep where dreaming often occurs and is thought to play a role in learning, memory, and mood regulation.

For bodybuilders, good quality sleep is crucial for recovery and growth. During sleep, the body repairs the muscle tissue damaged during workouts, and growth hormone, which is essential for muscle growth, is also released during sleep. By improving sleep quality, MK-677 can therefore support better recovery and muscle growth.

In conclusion, while MK-677 comes with its own set of caveats, it offers several benefits that can be particularly useful for bodybuilders, including increased water retention, increased appetite, and improved sleep quality.

MK-677 Dosage for Bodybuilding

When it comes to using MK-677 for bodybuilding, getting the dosage right is crucial. Too little, and you might not see the results you’re hoping for. Too much, and you could end up dealing with unwanted side effects. So, what’s the sweet spot?

Research suggests that a dosage of 25 milligrams per day is optimal for muscle growth and fat loss. This dosage is based on clinical studies, such as one published in the Journal of Clinical Endocrinology & Metabolism, which found that a daily dose of 25 milligrams of MK-677 significantly increased growth hormone and IGF-1 levels in the body.

But remember, everyone’s body is different, and what works for one person might not work for another. It’s always a good idea to start with a lower dose and gradually increase it, monitoring your body’s response along the way.

As for when to take MK-677, the timing can be quite flexible. Some people prefer to take it in the morning, while others prefer to take it at night. The key is consistency.

Choose a time that works for you and stick to it. Taking your dose at the same time each day can help maintain stable levels of the drug in your body, maximizing its effectiveness.

MK-677 Cycle Length and Timing

Now that we’ve covered dosage, let’s talk about cycle length and timing. How long should you take MK-677, and when is the best time to take it?

When it comes to cycle length, there’s no one-size-fits-all answer. Some bodybuilders prefer shorter cycles of 8–12 weeks, while others opt for longer cycles of 6–12 months. The right cycle length for you will depend on your goals, your experience with MK-677, and how your body responds to the drug.

A study published in the Annals of Internal Medicine found that MK-677 was well-tolerated over a 12-month period, suggesting that longer cycles could be safe and effective. However, it’s always a good idea to take a break after each cycle to give your body a chance to reset.

As for the best time to take MK-677, this will largely depend on your personal preference and schedule. Some people prefer to take it in the morning, while others prefer to take it at night. However, since MK-677 can increase hunger, some users find it beneficial to take it at night to avoid excessive daytime eating.

Remember, consistency is key. Choose a time that works for you and stick to it. This will help maintain stable levels of the drug in your body, maximizing its effectiveness.

When it comes to MK-677 dosage and cycle length, it’s all about finding what works best for you. Start with a lower dose, gradually increase it if needed, and choose a cycle length and timing that fits your goals and lifestyle. And as always, listen to your body and adjust as needed.

MK-677 vs. HGH (Human Growth Hormone) for Bodybuilding

In the world of bodybuilding and fitness, MK-677 and Human Growth Hormone (HGH) are often compared. Both are known for their ability to stimulate muscle growth and fat loss, but they work in different ways and come with their own sets of benefits and drawbacks. Let’s dive in and compare the two. 


As we’ve discussed, MK-677, or Ibutamoren, is a growth hormone secretagogue. It works by mimicking the action of the hormone ghrelin, tricking the brain into releasing growth hormone. This leads to increased levels of growth hormone and IGF-1 in the body, which can promote muscle growth, fat loss, improved bone density, and anti-aging effects.

One of the main benefits of MK-677 is that it’s orally active. This means you can simply swallow a pill, rather than having to deal with injections. It also leads to a more sustained release of growth hormone, providing a steady increase in hormone levels throughout the day.

However, MK-677 is not without its drawbacks. It can increase appetite, which might lead to weight gain if not managed properly. It can also lead to increased blood sugar levels, so it’s important to monitor your blood sugar if you’re using MK-677.

HGH (Human Growth Hormone)

HGH, on the other hand, is a hormone that’s naturally produced by the pituitary gland. It plays a key role in growth, body composition, cell repair, and metabolism. Synthetic HGH is often used in medicine to treat children with growth disorders and adults with growth hormone deficiency.

In the context of bodybuilding, HGH is often used for its ability to promote muscle growth and fat loss. However, unlike MK-677, HGH is typically administered via injection. This can be a drawback for those who are uncomfortable with needles.

Another key difference is that HGH injections typically lead to a more rapid increase in growth hormone levels as compared to MK-677. This can be beneficial for achieving quick results, but it also comes with a higher risk of side effects. These can include joint and muscle pain, carpal tunnel syndrome, and increased insulin resistance.

In terms of benefits, HGH can lead to significant improvements in body composition, muscle growth, and recovery. However, it’s important to note that these benefits typically come with higher doses, which can increase the risk of side effects.

Both MK-677 and HGH offer unique benefits for bodybuilders. MK-677 provides a more convenient and sustained release of growth hormone, while HGH can lead to more rapid results. However, both come with their own sets of drawbacks, and it’s important to consider these when deciding which is right for you.

My Bodybuilding Experience with MK-677

When I first decided to try MK-677, I was excited but also a bit apprehensive. I had heard a lot about its potential benefits for bodybuilding, but I also knew that it came with its own set of caveats.

One of the first things I noticed was that MK-677 made me extremely lethargic when I took it in the mornings. I heard of a few people who take it in the morning, but personally, I found that taking it at night worked best for me. It actually helped me get better sleep, although I did feel a bit cloudy and lethargic the next morning.

To combat this, I found it beneficial to take days off. A doctor from Transcend recommended a schedule of five days on and two days off, which I followed during my bulking phase.

I also found it helpful to cycle off after a certain period. Ten weeks seemed to be a standard, but everyone is different, so it’s important to monitor your own response.

One of the most important things I learned about MK-677 is the importance of monitoring your blood glucose. Elevated blood glucose over a long period of time can lead to diabetes, so I bought a blood glucose monitor from Amazon to keep track of my levels. I aimed for blood sugar below 100 nanograms per deciliter if taken fasted in the morning or below 140 if taken nonfasted.

To help combat the increase in insulin resistance, I tried adding fish oil supplementation and BERBERINE, an over-the-counter substance found in tree bark that acts similarly to metformin. However, I found that BERBERINE increased my stomach discomfort and flatulence.

One of the most noticeable effects of MK-677 was the increase in hunger. This was great for bulking, but not so much for cutting. If you’re prone to gaining weight easily, you might want to reconsider using MK-677. However, if you’re a hard gainer, this could be a useful tool.

I also noticed a lot of muscle fullness and some amazing pumps in the gym. However, MK-677 did cause some water retention. If I wanted to look dry for the weekend, I would take Thursday and Friday off from MK-677.

Overall, there are both pros and cons to using MK-677. It’s important to monitor your blood glucose and be aware of potential side effects. But for me, the benefits outweighed the drawbacks.

I experienced amazing pumps in the gym, great sleep, and it helped me build more muscle while keeping my fat gain low. It’s not something I would take during a cut, but it’s definitely been beneficial during my bulk.

Bodybuilders who use it the best way, consider taking it for approximately ten weeks, following a schedule of five days on and two days off. After the ten-week period, they plan to cycle off. Some obtain their MK-677 prescription from HRT Clinics like Transcend HRT, which also supplies TRT, HRT medications, and other men’s optimization treatments..

Real Users Experiences on Using MK-677 for Bodybuilding & Muscle Gains

Here is a collection of how others have felt while using MK-677 for bodybuilding

  1. Some users from the PEDs subreddit shared that they noticed size and strength gains after using MK-677 on and off for a couple of months. They didn’t experience any water retention and were able to get deeper sleep with the addition of magnesium. However, they mentioned that they still couldn’t stay asleep for 8 hours, indicating that while MK-677 may improve sleep quality, it might not necessarily extend sleep duration for everyone.

2). Some users loved MK-677, despite it elevating their blood glucose levels. They found it beneficial for gains, reporting an 8kg weight gain and a significant increase in their bench press over a couple of months. They also noticed improvements in their leg size. Interestingly, they also reported that their shoulders, which used to click and get sore, now have excellent smooth range of motion with no clicking, suggesting potential benefits of MK-677 in joint health.

3). Some users shared that MK-677 made them super hungry, which they found beneficial for their bulking phase. They also reported experiencing the deepest sleep and having the craziest dreams while on MK-677. However, they did caution that it’s smart to get a blood glucose monitor and not to take MK-677 for longer than a couple of months due to its effect on blood glucose levels.

4). Some users reported using MK-677 during their Post Cycle Therapy (PCT) to maintain gains, and they found it worked wonders for that purpose.

5). MK-677 made some users extremely hungry, which they found beneficial for their bulking phase. However, they also experienced significant water retention, which caused discomfort during certain exercises. They also reported feeling lazy while on MK-677.

6). One user reported that MK-677 made their vision blurry, which they attributed to increased blood pressure and water retention. They didn’t notice any benefits from using MK-677.

7). A user from the sarmssourcetalk subreddit reported that MK-677 helped them achieve the best definition they’ve ever had during a cut. They experienced increased hunger, but no other side effects. They also reported feeling a bit lazy during the first few days of use but quickly adapted.

Key Takeaways on MK-677 Benefits & people’s experiences using Ibutamoren for bodybuilding

Based on these user experiences, here are some key takeaways:

  1. MK-677 may aid in muscle growth and strength gains, as reported by several users.
  2. Some users have reported improved sleep quality while using MK-677.
  3. MK-677 may increase appetite, which could be beneficial for those looking to bulk.
  4. Monitoring blood glucose levels is recommended due to MK-677’s potential effect on blood glucose.
  5. MK-677 may help maintain muscle gains during PCT, as reported by one user.
  6. Some users have reported increased hunger while using MK-677, which could be beneficial for those looking to bulk.
  7. Water retention and increased blood pressure are potential side effects of MK-677, as reported by several users.
  8. Some users have reported feeling lazy or experiencing blurry vision while using MK-677.
  9. Individual experiences with MK-677 can vary greatly, and it’s important to listen to your body and adjust dosage or discontinue use if necessary.

It’s important to remember that these are individual experiences, and MK-677 may not work the same way for everyone, when it comes to bodybuilding benefits. Always consult with a healthcare professional before starting any new supplement regimen.


Ron Males, a seasoned bodybuilder and sports performance enhancement specialist, is known for his unique perspective on the parallels between sports and sex. With a foundation in personal experience and comprehensive research on performance enhancement supplements, testosterone boosters, and muscle building supplements, Ron is dedicated to providing accurate information to counteract widespread misinformation. His interests extend to technology and biohacking, with a focus on optimizing all aspects of human life. Ron advocates for the use of herbs, performance-enhancing drugs, and other substances to boost performance in various settings, from corporate environments to physical fitness and daily life. He is always seeking innovative methods to expand human capabilities. As a supplement reviewer at, Ron uses his extensive knowledge to analyze supplements, providing readers with reliable, in-depth reviews to guide their decisions. His first-hand experience with several bodybuilding supplements, and understanding of herbs & bio-hacking makes him an invaluable asset to the community. Read more about him.

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Dr. Aleksandar Grbovic is a highly experienced medical doctor specializing in cardiovascular and diabetes medications, with a notable academic tenure at the University of Belgrade's Faculty of Medicine. He has a significant association with the Institute of Occupational Medicine "Serbian Railways," a primary care facility serving over 100,000 patients across Serbia. His medical expertise extends to Radiology, and he has contributed to the development of educational materials for US medical board exams. Dr. Grbovic is also a freelance medical writer, aiming to bridge the communication gap between doctors and patients by simplifying complex medical topics. As a Senior Medical Reviewer at, he uses his extensive knowledge to provide accurate and understandable health information to the public. Read more about him.